Hawthorn (Crataegus spp.) from botanical source to phytopreparations

The usage of hawthorn preparations has a long history in the traditional treatment heart failure, which is considered as inability weakened to supply peripheral tissues with required amount oxygen and nutrients. leaf, flower, fruit hawthorn, due presence bioactive compounds such flavonoids, procyanidins, organic acids, amines, etc., are showing wide range effects on cardiovascular system. leaf flower have positive monograph Commission E, well EMA monograph, but only for use. Numerous clinical studies been conducted evaluate beneficial dry extracts diseases. There large number phytopreparations various galenic forms market trade. According recent guidelines, monotherapy failure not recommended. Instead, it should be used an adjunct therapy.